May 28, 2009
Happy hour gene
I think this paper presents one of the funniest names for a Drosophila mutant: Ammon B. Corl et al, Happyhour, a Ste20 Family Kinase, Implicates EGFR Signaling in Ethanol-Induced Behaviors, Cell 137, 949–960, May 29, 200
The happyhour mutants were not as sedated by alcohol as their wild-type relatives. If the receptor involved were inhibited by erlotinib, flies and mice instead became more sensitive. Rats with this treatment didn't drink as much alcohol. Lots of intriguing applications.
Posted by Anders3 at May 28, 2009 05:15 PMComments